Adapalene, Retinoid RARb, g agonist (TBI1011)

Description

Product Details

Formal Name: 6-[3-(1-Adamantyl)-4-methoxyphenyl]-2-naphthoic acid

Alternate Names: CD271

Molecular Formula: C₂₈H₂₈O₃

Formula Weight: 412.53

CAS Number: 106685-40-9

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 3 mg/ml) or in DMF (up to 6 mg/ml).

Storage: RT

Stability: ≥ 1 year.

Applications

Retinoid RARb, g agonist

Functions

Stable analog of retinoic acid that acts as a selective agonist for RARß and RARγ. Also inhibits proliferation and induces apoptosis in colorectal cancer cells in culture.

Application Procedures

First dissolved in DMSO (up to 3 mg/ml) or in DMF (up to 6 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or DMF may be stored at -20°C for up to 3 months.