3-Cyano-7-ethoxycoumarin, Cytochrome P450 Fluorescent substrate (TBI1440)

Description

Product Details

Formal Name: 7-Ethoxy-2-oxo-2H-1-benzopyran-3-carbonitrile

Molecular Formula: C₁₂H₉NO₃

Formula Weight: 215.2

CAS Number: 117620-77-6

Purity: >98%

Formulation: Powder

Solubility: Soluble in DMSO (up to 20 mg/ml with warming) or in Ethanol (up to 3 mg/ml with warming)

Storage: Room temperature / protect from light

Stability: ≥ 1 year.

Applications

Cytochrome P450 Fluorescent substrate

Functions

Fluorescent substrate for cytochrome P450. Excitation/emission = 408/455 nm. May be used for CYP1A2 and CYP2C19 in intact cells. Cell permeable.

Application Procedures

First dissolved in DMSO (up to 20 mg/ml with warming) or in Ethanol (up to 3 mg/ml with warming), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.