6,7-ADTN HBr, Dopamine D1 agonist (TBI1607)

Description

Product Details

Formal Name: (+/-)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene hydrobromide

Alternate Names: 6-Amino-5,6,7,8-tetrahydronaphthalene-2,3-diol hydrobromide (racemic); NSC-287353

Molecular Formula: C₁₀H₁₃NO₂ HBr

Formula Weight: 260.13

CAS Number: 13575-86-5

Purity: >98%

Formulation: Powder

Solubility: Soluble in water (up to 25 mg/ml)

Storage: -20°C

Stability: ≥ 1 year.

Applications

Dopamine D1 agonist

Functions

A broad spectrum dopamine receptor agonist. Demonstrates a marked selectivity for the human dopamine D3 receptor. 6,7-ADTN and psychostimulants such as cocaine and amphetamine reduce excitatory synaptic transmission in the nucleus accumbens by activating presynaptic dopamine receptors.

Application Procedures

First dissolved in water (up to 25 mg/ml), then diluted to aqueous buffer. Solutions in water may be stored at -20°C for up to 3 months.