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GenDEPOT  |  SKU: BC020-101

Cyclosporin A, >99%

$132.00
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Product Description


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GenDEPOT

Cyclosporin A, >99%

From $132.00

A fungal metabolite possessing potent immunosuppressive properties. It inhibits the T-cell receptor signal transduction pathway via the formation of cyclosporin A−cyclophilin complex that inhibits calcineurin (protein phosphatase 2B). Inhibits nitric oxide synthesis induced by interleukin 1α, lipopolysaccharides and TNFα. Can block cytochrome c release from mitochondria.

Store at -20℃

IC50 7 nM
Targets Calcineurin
Solubility 100 mg/mL warmed (83.15 mM) in DMSO

Size

  • 1g
  • 5g
  • 10g
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